ATBC is a suitable material for medical devices and medical polyvinyl chloride assemblies. Tri-n-butyl acetyl citrate is a substitute for dioctyl phthalate (DOP) and used in medical rubber products like gloves and tubes. ATBC is non-toxic, low-migration and biocompatibility, making it very suited for medical devices. ATBC is also commonly used as a plasticizer in PVC medical products. Because of its thermal stability and low volatility, ATBC can make PVC products more flexible and transparent, while retaining flexural integrity at low temperatures. This makes it very useful in medical packaging applications like infusion tubes and plasma bags. Tri-n-butyl acetyl citrate is also used for coating pharmaceutical capsules, tablets and granules. It can cover up the drug taste, create prolonged release and enteric action, thus increasing drug compliance in patients. Apart from these uses, tri-n-butyl acetyl citrate can also be used to modify other medical materials, including polylactic acid (PLLA) materials. Citrate plasticizers, it turns out, are capable of effectively lowering the glass transition temperature of PLLA, making it easier to process, and overcoming the issue of brittle fracture. A non-toxic, non-polluting, water-resistant, and cold-resistant material, acetyl tributyl citrate has found applications in many medical products, particularly rubber products, PVC products and drug coatings, as a safe and trusted material for the medical community.